abstract：BACKGROUND:In order to investigate the epidemiology, molecular characteristics, and distribution of extended-spectrum β-lactamase (ESBL)- and AmpC-producing Escherichia coli from community-onset infections in Chinese county hospitals. METHODS:E. coli isolates were collected from patients with community-onset infection...

journal_title：BMC infectious diseases

authors： Zhang J,Zheng B,Zhao L,Wei Z,Ji J,Li L,Xiao Y

更新日期：2014-12-03 00:00:00

abstract：BACKGROUND:While cultivation of pathogens represents a foundational diagnostic approach in the study of infectious diseases, its value for the confirmation of clinical diagnosis of Buruli ulcer is limited by the fact that colonies of Mycobacterium ulcerans appear only after about eight weeks of incubation at 30°C. Howe...

journal_title：BMC infectious diseases

authors： Bratschi MW,Bolz M,Grize L,Kerber S,Minyem JC,Um Boock A,Yeboah-Manu D,Ruf MT,Pluschke G

更新日期：2014-11-30 00:00:00

abstract：BACKGROUND:The increasing occurrence of multidrug resistant (MDR) bacteria arises at a time when there is a lack of antibiotics active against these pathogens and few new antimicrobials are in the pipelines of the pharmaceutical industry. Treatment of ventilator-associated pneumonia (VAP) caused especially by MDR Gram-...

journal_title：BMC infectious diseases

authors： Garnacho-Montero J,Corcia-Palomo Y,Amaya-Villar R,Martin-Villen L

更新日期：2014-11-28 00:00:00

abstract：BACKGROUND:Viral central nervous system (CNS) infections are common in countries where malaria is endemic but, due to limited laboratory facilities, few studies have systematically examined the prevalence and clinical consequences of the presence of viruses in cerebrospinal fluid (CSF) from children with suspected CNS ...

journal_title：BMC infectious diseases

authors： Laman M,Hwaiwhanje I,Bona C,Warrel J,Aipit S,Smith D,Noronha J,Siba P,Mueller I,Betuela I,Davis TM,Manning L

更新日期：2014-11-26 00:00:00

abstract：BACKGROUND:Tétanos Quick Stick® (TQS) is a test for tetanus immunity screening for wounded patients in emergency departments (EDs), but represents additional costs compared with a medical interview on vaccination history. The study objective was to assess the effectiveness and cost of the TQS in French EDs. METHODS:We...

journal_title：BMC infectious diseases

authors： N'Diaye DS,Schwarzinger M,Obach D,Poissy J,Matheron S,Casalino E,Yazdanpanah Y

更新日期：2014-11-19 00:00:00

abstract：BACKGROUND:We estimated the nationwide burden of nosocomial S. aureus bloodstream infection (SA-BSI), a major cause of nosocomial infection, in South Korea. METHODS:To evaluate the nationwide incidence of nosocomial SA-BSI, cases of SA-BSI were prospectively collected from 22 hospitals with over 500 beds over 4?months...

journal_title：BMC infectious diseases

authors： Kim CJ,Kim HB,Oh MD,Kim Y,Kim A,Oh SH,Song KH,Kim E,Cho Y,Choi Y,Park J,Kim BN,Kim NJ,Kim KH,Lee E,Jun JB,Kim Y,Kiem S,Choi H,Choo E,Sohn KM,Lee S,Chang H,Bang J,Lee S,Lee J,Park S,Jeon M,Yun N,K

更新日期：2014-11-14 00:00:00

abstract：BACKGROUND:To better understand potential transmission risks from contact with the body fluids of children, we monitored the presence and amount of CMV shedding over time in healthy CMV-seropositive children. METHODS:Through screening we identified 36 children from the Atlanta, Georgia area who were CMV-seropositive, ...

journal_title：BMC infectious diseases

authors： Cannon MJ,Stowell JD,Clark R,Dollard PR,Johnson D,Mask K,Stover C,Wu K,Amin M,Hendley W,Guo J,Schmid DS,Dollard SC

更新日期：2014-11-13 00:00:00

abstract：BACKGROUND:Chlamydia trachomatis is a pathogen of worldwide importance, causing more than 100 million cases of sexually transmitted infections annually. Whole-genome sequencing is a powerful high resolution tool that can be used to generate accurate data on bacterial population structure, phylogeography and mutations a...

journal_title：BMC infectious diseases

authors： Christiansen MT,Brown AC,Kundu S,Tutill HJ,Williams R,Brown JR,Holdstock J,Holland MJ,Stevenson S,Dave J,Tong CY,Einer-Jensen K,Depledge DP,Breuer J

更新日期：2014-11-12 00:00:00

abstract：BACKGROUND:This study aims to investigate the clinical features of invasive community-acquired Staphylococcus aureus (CA-SA) infection in Chinese children and analyze its molecular features. METHODS:Clinical data and invasive CA-SA isolates were prospectively collected. Pediatric risk of mortality (PRISM) score was us...

journal_title：BMC infectious diseases

authors： Qiao Y,Ning X,Chen Q,Zhao R,Song W,Zheng Y,Dong F,Li S,Li J,Wang L,Zeng T,Dong Y,Yao K,Yu S,Yang Y,Shen X

更新日期：2014-11-07 00:00:00

abstract：BACKGROUND:Collecting adequate information on key epidemiological indicators is a prerequisite to informing a public health response to reduce the impact of hepatitis C virus (HCV) infection in Malaysia. Our goal was to overcome the acute data shortage typical of low/middle income countries using statistical modelling ...

journal_title：BMC infectious diseases

authors： McDonald SA,Mohamed R,Dahlui M,Naning H,Kamarulzaman A

更新日期：2014-11-07 00:00:00

abstract：BACKGROUND:Antiretroviral therapy markedly reduced mortality in HIV-infected individuals. However, in the previous studies, up to 50% of patients are compelled to modify their regimen in middle and low-income countries where salvage drug is still limited. This cohort study aimed to investigate the incidence and predict...

journal_title：BMC infectious diseases

authors： Tsuchiya N,Pathipvanich P,Wichukchinda N,Rojanawiwat A,Auwanit W,Ariyoshi K,Sawanpanyalert P

更新日期：2014-10-30 00:00:00

abstract：BACKGROUND:The usefulness of sputum Gram stain in patients with community-acquired pneumonia (CAP) is controversial. There has been no study to evaluate the diagnostic value of this method in patients with healthcare-associated pneumonia (HCAP). The purpose of this study was to evaluate the usefulness of sputum Gram st...

journal_title：BMC infectious diseases

authors： Fukuyama H,Yamashiro S,Kinjo K,Tamaki H,Kishaba T

更新日期：2014-10-18 00:00:00

abstract：BACKGROUND:Antimicrobial resistance is an increasing concern in ICUs worldwide. Infection with an antibiotic resistant (ABR) strain of an organism is associated with greater mortality than infection with the non-resistant strain, but there are few data assessing whether being admitted to an intensive care unit (ICU) wi...

journal_title：BMC infectious diseases

authors： Hanberger H,Antonelli M,Holmbom M,Lipman J,Pickkers P,Leone M,Rello J,Sakr Y,Walther SM,Vanhems P,Vincent JL,EPIC II Group of Investigators.

更新日期：2014-09-22 00:00:00

abstract：BACKGROUND:A decline in hemoglobin (Hb) concentration during antiviral therapy in chronic hepatitis C (CHC) is a serious side effect. It may compel to dose reduction or even termination of antiviral treatment. The activation of erythropoietin (EPO) synthesis as a physiological response to anemia and its relation to a g...

journal_title：BMC infectious diseases

authors： Amanzada A,Goralczyk AD,Reinhardt L,Moriconi F,Cameron S,Mihm S

更新日期：2014-09-17 00:00:00

abstract：BACKGROUND:Changes of miRNAs in exosome have been reported in different disease diagnosis and provided as potential biomarkers. In this study, we compared microRNA profile in exosomes in 5 MHFMD and 5 ESHFMD as well as in 5 healthy children. METHODS:Different expression of miRNAs in exosomes across all the three group...

journal_title：BMC infectious diseases

authors： Jia HL,He CH,Wang ZY,Xu YF,Yin GQ,Mao LJ,Liu CW,Deng L

更新日期：2014-09-17 00:00:00

abstract：BACKGROUND:Cytopenias are the most common HIV-associated hematological abnormality. Cytopenias have been associated with several factors including sex, race/ethnicity, geographical location and comorbidities such as tuberculosis, hepatitis B infection, fever and oral candidiasis. Cytopenias become more prevalent as HIV...

journal_title：BMC infectious diseases

authors： Kyeyune R,Saathoff E,Ezeamama AE,Löscher T,Fawzi W,Guwatudde D

更新日期：2014-09-10 00:00:00

abstract：BACKGROUND:The potential impact of an influenza pandemic can be assessed by calculating a set of transmissibility parameters, the most important being the reproduction number (R), which is defined as the average number of secondary cases generated per typical infectious case. METHODS:We conducted a systematic review t...

journal_title：BMC infectious diseases

authors： Biggerstaff M,Cauchemez S,Reed C,Gambhir M,Finelli L

更新日期：2014-09-04 00:00:00

abstract：BACKGROUND:Introduction of Xpert® MTB/RIF assay has revolutionalised the diagnosis of tuberculosis (TB) by simultaneously detecting the bacteria and resistance to rifampicin (rif), a surrogate marker for multi-drug resistant TB (MDR-TB) as well as one of the principal first-line anti-tuberculosis drugs. In general, rpo...

journal_title：BMC infectious diseases

authors： Mboowa G,Namaganda C,Ssengooba W

更新日期：2014-09-04 00:00:00

abstract：BACKGROUND:Facial lipoatrophy is a frequently reported condition associated with use of antiretroviral (ARV) drugs. Poly-L-lactic acid (PLLA) acid has been used to correct facial lipoatrophy in people with HIV since 2004 both in Europe and the United States. The objective of this study was to establish, in real life co...

journal_title：BMC infectious diseases

authors： Duracinsky M,Leclercq P,Herrmann S,Christen MO,Dolivo M,Goujard C,Chassany O

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Fatigue is a common symptom of chronic hepatitis C virus (HCV) infection and a frequent side-effect of peginterferon/ribavirin (PR) therapy for HCV. This study evaluated the impact of adding the oral HCV NS3/4A protease inhibitor simeprevir to PR on patient-reported fatigue and health status among patients w...

journal_title：BMC infectious diseases

authors： Scott J,Rosa K,Fu M,Cerri K,Peeters M,Beumont M,Zeuzem S,Evon DM,Gilles L

更新日期：2014-08-26 00:00:00

abstract：BACKGROUND:The China-Myanmar border is a particularly interesting region that has very high prevalence of and considerable diversity of HIV-1 recombinants. Due to the transient nature of their work, long-distance truck drivers (LDTDs) have a comparatively high potential to become infected with HIV-1 and further spread ...

journal_title：BMC infectious diseases

authors： Zhou YH,Liang YB,Pang W,Qin WH,Yao ZH,Chen X,Zhang C,Zheng YT

更新日期：2014-08-26 00:00:00

abstract：BACKGROUND:The federal state of Hesse, Germany, introduced a laboratory-based reporting scheme for carbapenem-resistant organisms (CROs). METHOD:The results of the first year of mandated reporting of CROs from April 2012 through March 2013 to the Public Health Authority of Frankfurt/Main, responsible for a population ...

journal_title：BMC infectious diseases

authors： Kleinkauf N,Hausemann A,Kempf VA,Gottschalk R,Heudorf U

更新日期：2014-08-19 00:00:00

abstract：BACKGROUND:The durability of off-treatment virologic responses has not been fully elucidated in chronic hepatitis B (CHB) patients who have previously achieved complete virologic suppression with nucleos(t)ide analog (NA) therapy. This study aimed to assess off-treatment virologic relapse rates and to characterize the ...

journal_title：BMC infectious diseases

authors： Sohn HR,Min BY,Song JC,Seong MH,Lee SS,Jang ES,Shin CM,Park YS,Hwang JH,Jeong SH,Kim N,Lee DH,Kim JW

更新日期：2014-08-13 00:00:00

abstract：BACKGROUND:Over the last decade, increases in the number of outbreaks of hand, foot and mouth disease (HFMD) have shifted the disease into the public health spotlight in China. Children under the age of five years are particularly susceptible, with fatalities recorded. However, estimating the burden of HFMD has been di...

journal_title：BMC infectious diseases

authors： Wang X,Wu X,Jia L,Li X,Li J,Li S,Qian H,Wang Q

更新日期：2014-08-12 00:00:00

abstract：BACKGROUND:While the prevalence of multidrug-resistant (MDR) tuberculosis (TB) is high among children in the Western Cape of South Africa, the psychosocial implications of treatment for children with MDR-TB remain poorly understood. We sought to explore how MDR-TB and its treatment impact children on an individual, fam...

journal_title：BMC infectious diseases

authors： Franck C,Seddon JA,Hesseling AC,Schaaf HS,Skinner D,Reynolds L

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Emphysematous pyelonephritis (EPN) is a severe necrotizing infection of the renal parenchyma and perirenal tissues that is caused by gas-producing bacterial pathogens. Percutaneous drainage is now the gold standard of definitive management. The aim of this study is to analyze the predictors associated with f...

journal_title：BMC infectious diseases

authors： Lu YC,Chiang BJ,Pong YH,Huang KH,Hsueh PR,Huang CY,Pu YS

更新日期：2014-07-29 00:00:00

abstract：BACKGROUND:Alcohol use has a detrimental impact on the HIV epidemic, especially in sub-Saharan Africa. HIV counseling and testing (HCT) may provide a contact opportunity to intervene with hazardous alcohol use; however, little is known about how alcohol consumption changes following HCT. METHODS:We utilized data from ...

journal_title：BMC infectious diseases

authors： Hahn JA,Fatch R,Wanyenze RK,Baveewo S,Kamya MR,Bangsberg DR,Coates TJ

更新日期：2014-07-20 00:00:00

abstract：BACKGROUND:The live attenuated 17DD Yellow Fever vaccine is one of the most successful prophylactic interventions for controlling disease expansion ever designed and utilized in larger scale. However, increase on worldwide vaccine demands and manufacturing restrictions urge for more detailed dose sparing studies. The e...

journal_title：BMC infectious diseases

authors： Campi-Azevedo AC,de Almeida Estevam P,Coelho-Dos-Reis JG,Peruhype-Magalhães V,Villela-Rezende G,Quaresma PF,Maia Mde L,Farias RH,Camacho LA,Freire Mda S,Galler R,Yamamura AM,Almeida LF,Lima SM,Nogueira RM,Silva Sá GR,Hoka

更新日期：2014-07-15 00:00:00

abstract：BACKGROUND:Hypervariable region 1 (HVR1) contained within envelope protein 2 (E2) gene is the most variable part of HCV genome and its translation product is a major target for the host immune response. Variability within HVR1 may facilitate evasion of the immune response and could affect treatment outcome. The aim of ...

journal_title：BMC infectious diseases

authors： Cortés KC,Zagordi O,Perlejewski K,Laskus T,Maroszek K,Bukowska-Ośko I,Pawełczyk A,Płoski R,Berak H,Horban A,Radkowski M

更新日期：2014-07-13 00:00:00

abstract：BACKGROUND:Hemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses is a serious public health problem in China. The National Notifiable Disease Surveillance System (NNDSS) was established online by China CDC in 2004 and rodent surveillance sites were adjusted to 40 sites in 22 provinces in 2005. Here we ana...

journal_title：BMC infectious diseases

authors： Zhang S,Wang S,Yin W,Liang M,Li J,Zhang Q,Feng Z,Li D

更新日期：2014-07-11 00:00:00

abstract：BACKGROUND:Qinghai-Tibetan Plateau of China is known to be the plague endemic region where marmot (Marmota himalayana) is the primary host. Human plague cases are relatively low incidence but high mortality, which presents unique surveillance and public health challenges, because early detection through surveillance ma...

journal_title：BMC infectious diseases

authors： Qian Q,Zhao J,Fang L,Zhou H,Zhang W,Wei L,Yang H,Yin W,Cao W,Li Q

更新日期：2014-07-10 00:00:00

abstract：BACKGROUND:Rituximab, a monoclonal antibody directed against CD20, is approved for the treatment of CD20-positive B-cell Non-Hodgkin's lymphoma and rheumatologic disorders. Due to its potent activity in depleting CD20-positive lymphocytes, the influence on opportunistic infections is still under discussion. Thus, we an...

journal_title：BMC infectious diseases

authors： Nissen JC,Hummel M,Brade J,Kruth J,Hofmann WK,Buchheidt D,Reinwald M

更新日期：2014-07-03 00:00:00

abstract：BACKGROUND:The different laboratory methods used in the diagnosis of congenital toxoplasmosis have variable sensitivity and specificity. There is no evidence to prove that maternal treatment reduces the risk of fetal infection. The purpose of this study was to assess methods for the confirmation of congenital toxoplasm...

journal_title：BMC infectious diseases

authors： Rodrigues IM,Costa TL,Avelar JB,Amaral WN,Castro AM,Avelino MM

更新日期：2014-06-24 00:00:00

abstract：BACKGROUND:Q fever is caused by the intracellular bacterium Coxiella burnetii. Initial infection can present as acute Q fever, while a minority of infected individuals develops chronic Q fever endocarditis or vascular infection months to years after initial infection. Serology is an important diagnostic tool for both a...

journal_title：BMC infectious diseases

authors： Schoffelen T,den Broeder AA,Nabuurs-Franssen M,van Deuren M,Sprong T

更新日期：2014-06-15 00:00:00

abstract：BACKGROUND:Surgical site infections following coronary artery bypass graft (CABG) procedures pose substantial burden on patients and healthcare systems. This study aims to describe the incidence of surgical site infections and causative pathogens following CABG surgery over the period 2003-2012, and to identify risk fa...

journal_title：BMC infectious diseases

authors： Si D,Rajmokan M,Lakhan P,Marquess J,Coulter C,Paterson D

更新日期：2014-06-10 00:00:00

abstract：BACKGROUND:Drug resistant organisms pose an increasing threat to the successful treatment of common infections. Understanding colonization patterns of these bacteria is important for effective antibiotic treatment and infection control guidelines. METHODS:A prospective observational study was performed to determine th...

journal_title：BMC infectious diseases

authors： Young BE,Lye DC,Krishnan P,Chan SP,Leo YS

更新日期：2014-06-02 00:00:00

abstract：BACKGROUND:In high-income settings, the spectrum of morbidity and mortality experienced by Human Immunodeficiency Virus (HIV)-infected individuals receiving combination antiretroviral therapy (cART) has switched from predominantly AIDS-related to non-AIDS-related conditions. In the context of universal access to care, ...

journal_title：BMC infectious diseases

authors： Luz PM,Bruyand M,Ribeiro S,Bonnet F,Moreira RI,Hessamfar M,Campos DP,Greib C,Cazanave C,Veloso VG,Dabis F,Grinsztejn B,Chêne G,IPEC\/FIOCRUZ Cohort and the Aquitaine ANRS C03 Study Group.

更新日期：2014-05-21 00:00:00

abstract：BACKGROUND:Erysipelas is a common infection that often recurs, but the impact of specific risk factors for reoccurrence remains elusive. In the present study we aimed at clarifying predisposing conditions for reoccurrence. METHODS:Medical records were reviewed from all patients ≥18 years of age diagnosed with erysipel...

journal_title：BMC infectious diseases

authors： Inghammar M,Rasmussen M,Linder A

更新日期：2014-05-18 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the epidemiology and resistance of methicillin-resistant Staphylococcus aureus (MRSA) isolates from long-term care facilities (LTCF) residents and to analyze the potential risk factors for MRSA occurrence, defined as MRSA colonization and/or infection. METHODS:Point ...

journal_title：BMC infectious diseases

authors： Romaniszyn D,Pobiega M,Wójkowska-Mach J,Chmielarczyk A,Gryglewska B,Adamski P,Heczko PB,Ochońska D,Bulanda M

更新日期：2014-05-18 00:00:00

abstract：BACKGROUND:A vaccine matched to a newly emerged pandemic influenza virus would require a production time of at least 6 months with current proven techniques, and so could only be used reactively after the peak of the pandemic. A pre-pandemic vaccine, although probably having lower efficacy, could be produced and used p...

journal_title：BMC infectious diseases

authors： Halder N,Kelso JK,Milne GJ

更新日期：2014-05-16 00:00:00